These experimental results can be explained by analytically calcu

These experimental results can be explained by analytically calculating

the anisotropic magnetoresistance effect induced by the motion of the vortex core. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3536390]“
“During investigations conducted within two years (2007 – 2009) 30 natural cenopopulations that were found, confirmed medicinal plants that can be used in the treatment of pediatric diseases. It was systematically studied life forms and distribution of 50 families, 94 genera and 97 species of medicinal plants widely spread in Azerbaijan flora which are used in the treatment of pediatric diseases. It was determined that the majority of medicinal plants contains grasses (71%, 69 species). Among them, perennials are characterized with the highest number (48 species, 49.5%), annuals with medium see more (12 species, 12.4%) and biennials with the least number (9 species, 9.3%). Profoundly described plant resources and role in the medicine of species such as, Berberis vulgaris, Crataegus pentagyna, Althaea officinalis, Hippophae rhamnoides, Inula helenium, Vaccinium myrtillis and Vaccinium vitis idaea detected and confirmed the area of distribution of medicinal plants, their vegetation phase and collected parts with priorities used in the treatment of pediatric diseases.”
“The present

article endeavors to synthesize new polyamides via direct polycondensation of various diamines [hexamethylene diamine, rho-phenylene diamine, 2,5-bis(m-aminobenzylidene) cyclopentanone, and 2,6-bis (m-aminobenzylidene) cyclohexanone] with different bis (carboxy-substituted) hydrazines such as [1,2-bis(3-carboxy acrylyl) hydrazine and 1,2-bis(3-carboxybenzoyl) hydrazine]. The polycondensation reaction of 1,2-bis(3-p-hydroxyanilide acrylyl) hydrazine with the same bis(carboxy-substituted) hydrazines gave polyester amides. The poly-condensation process was run in the presence of CaCl(2), triethylphosphite, and pyridine as a catalyst. These polymers were characterized by FTIR, (1)H-NMR, solubility, TGA, DSC, X-ray, mechanical properties, and electrical conductivity. The electrical conductivity measurements showed that all new polymers show promise as insulators. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 122: 1152-1161, 2011″
“We present a new type of electro- and magneto-optical spatial light modulators (e-MOSLMs) utilizing the concept of photonic crystals (PCs) – such e-MOSLMs have a microcavity structure. They comprise a magneto-optical (MO) and electro-optical (EO) constituents that can control the direction of the polarization plane, when applying voltage and/or external magnetic fields. Optical spectra of e-MOSLMs were analyzed by using the matrix approach.

Ten samples

Ten samples selleck kinase inhibitor were obtained for the study from patients attending a fertility clinic. Once collected, the sperm samples were prepared by density gradient centrifugation and incubated with 11 different lubricants including positive and negative controls for 30 min at 37 A degrees C to mimic the temperature inside the female reproductive tract. Sperm motility, vitality and DNA fragmentation were assessed to determine

the effects of the lubricants on sperm function and DNA integrity.

Nine lubricants were investigated including Sylk (TM), Conceive PlusA (R), glycerol, Johnson’sA (R) Baby Oil, SAGEA (R) Culture Oil, YesA (R), Forelife (TM), MaybeBabyA (R) and Pre-seedA (R). The lubricant which had the best results in terms of vitality, at 92 %, was Pre-seedA (R) and the worst was Forelife (TM) with 28 % vitality. In terms

of motility, Pre-seedA (R) resulted in the highest percentage of spermatozoa with progressive motility at 86 % and Sylk (TM) resulted in the lowest percentage of progressively motile cells in the sample with 31 % of sperm progressively motile. There were no significant effects on DNA integrity.

Pre-seedA (R) was the lubricant which had the least negative effect ERK inhibitor on sperm function, with Conceive PlusA (R) a close second, due to the significantly higher sperm motility and vitality parameters measured following lubricant exposure.”
“Heart transplantation has evolved into ATM/ATR 抑制剂 review the treatment of choice for eligible patients with end-stage heart failure. Effective immunosuppression is critical to the success of this treatment, with the modern era beginning with the advent of cyclosporin A in the 1980s. In this Perspectives article,

the major prospective, randomized trials of immunosuppression after heart transplantation are briefly reviewed. These trials provided the setting for the 2011 TICTAC trial, in which combined immunosuppression was compared with monotherapy. The results of the study are discussed, as are the implications of these data for future research, including the importance of frameworks, the risks and benefits of changes in immunosuppression regimen, the future of funding for such research, and the selection of appropriate end points in trials of heart transplantation. The presupposed need for multidrug immunosuppression is challenged, and the potential efficacy and benefits of monotherapy are explored.”
“Aims We hypothesize that the expression of genes encoding vaginal smooth muscle (SM) contractile proteins is altered in patients with pelvic organ prolapse (POP) and is influenced by age and menopausal status. We aim to analyze the expression of SM-myosin heavy chain (MHY11), caldesmon (CALD1), SM gamma-actin (ACTG2), and tropomyosin (TPM1), in premenopausal and postmenopausal women with advanced POP and asymptomatic controls.

5% and 34 3% for QFT-G and 86 8% and 35 3% for QFT The three tes

5% and 34.3% for QFT-G and 86.8% and 35.3% for QFT. The three tests were of similar accuracy, sensitivity and specificity in diagnosing TB.

CONCLUSION: Our findings indicate that the TST and IGRAs could not discriminate between active

TB and MAC disease or latent TB infection in a TB-endemic area.”
“Objective: The aim of this study was to compare the early repair response of cartilage defects in trochlea (TR) and medial femoral condyle selleck (MFC) at 2-3 weeks after bone marrow stimulation.

Design: Bilateral full-thickness cartilage defects were generated in central trochlear groove and MFC of skeletally mature rabbits. Four subchondral perforations were made on each defect, either by micro-fracture to 2 mm deep, or by drilling to 2 mm or 6 mm deep. Rabbits were sacrificed either on Day 14 post-operatively or on Day 21. Defects were analyzed

by histology, stereology, histomorphometry and micro-computed tomography (CT). Intact femurs (N = 4) served as controls.

Results: Stromal cell density recruitment was similar in all defects, irrespective of defect location and surgical techniques used. There was a robust appearance of chondrocytes at Day 21 in TR defects with significantly higher volume fraction of chondrocytes in TR compared to MFC (P = 0.013). Chondrogenic foci were observed in marrow penetrating holes, with a significantly higher frequency and larger foci in TR vs MFC defects at Day 21 (P = 0.043 and P = 0.0014, respectively). Micro-CT analysis showed that deep drilling elicited significantly more mineralized bone fill compared to shallower perforations at 2 and 3 weeks repair (all at P <= 0.0008).

Conclusions: EPZ5676 cell line Bone marrow stimulation induced greater chondrogenesis in TR vs MFC defects in adult rabbits, with more chondrocytes and larger chondrogenic foci appearing in TR vs MFC on Day 21 post-operation. (C) 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.”
“SETTING : Medical units at an academic tertiary referral hospital in Southern India.

OBJECTIVE: To investigate the impact of solid culture on Lowenstein-Jensen medium on clinical decision making.

DESIGN: In a retrospective review of 150

culture-positive and 150 culture-negative AZD7762 cell line consecutively sampled tuberculosis (TB) suspects, treatment decisions were analysed at presentation, after the availability of culture detection results and after the availability of drug susceptibility testing (DST) culture results.

RESULTS: A total of 124 (82.7%) culture-positive patients and 35 (23.3%) culture-negative patients started anti-tuberculosis treatment prior to receiving their culture results; 101 patients (33.7%) returned for their results; two (1.3%) initiated treatment based on positive culture and no culture-negative patients discontinued treatment. DST was performed on 119 (79.3%) positive cultures: 30 (25.2%) showed any resistance, eight (6.7%) showed multidrug resistance and one (0.84%) showed extensively drug-resistant TB.


Conclusions: This study provides evidence to suppo


Conclusions: This study provides evidence to support the current clinical practice toward use of a 4-week neonatal ARV prophylaxis regimen.”
“Purpose of review

This review examines the literature on the ability of an epidural test dose to detect intravascular or intrathecal epidural catheter misplacement in the obstetric patient.

Recent findings

There is no consensus on the exact nature of the epidural P5091 cell line test dose in obstetrics, as no single regimen has been proven to be completely effective as an epidural test dose. The administration of a test dose is especially important in patients who may require the administration

of a large dose of local anesthetic such as for an emergency cesarean section. However, the accidental administration of an intended epidural therapeutic dose during labor analgesia, in either the intravascular or the intrathecal space, is not completely safe.


Gentle aspiration followed by an appropriate test dose, in epidural anesthesia for cesarean section, and careful observation of the patients in epidural labor analgesia increase the likelihood that an incorrectly placed catheter will be detected and that a harmful reaction to local anesthetics will be avoided.”
“Silver polyhedron coated electrospun nylon 6 nanofibrous membranes were produced using a nonhazardous and green electroless process. The process employed sodium citrate as

a complexing and reducing agent at 80 degrees WH-4-023 Angiogenesis inhibitor C, without the need of any surfactant or hazardous chemicals. PF-562271 concentration The novel nanofibrous membrane, produced under optimum conditions, demonstrated high infrared (IR) extinction and ultraviolet (UV) blocking and good water vapor permeability. It is expected to have wide potential application for thermal radiation shielding, UV blocking and IR camouflage. (c) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011″
“The work presented in this paper is concerned with the fundamental study of a damage detection principle in a reverberant medium, based on ambient acoustic noise correlation. The aim here is to theoretically investigate the sensitivity of the correlation of received signals

to a local defect. The acoustic reverberation in the medium is modeled by a random process and an empirical description of the defect behavior is deduced from its experimental characterization. A global parameter r, corresponding to the energy ratio between the change in the correlation function caused by the defect and the defect-free correlation, is defined and theoretically derived. It is shown to essentially depend on the reverberation properties of the medium and the relative positions of the noise source, the sensor(s) and the defect. The theoretical expression of r is experimentally validated in a particular 2D-case (metallic plate) and then used to define the detection range and the optimal placements of the sensors. (C) 2011 American Institute of Physics. [doi:10.1063/1.

The 3D scans were superimposed to determine postinjection changes

The 3D scans were superimposed to determine postinjection changes in volume and thickness. Results Although there was little change in the noninjected side over the experimental period, the mean volume and thickness of the injected side Sepantronium chemical structure at each time point clearly and statistically significantly decreased between preinjection and 4, 8, and 12weeks postinjection. Conclusion Unilateral BoNT-A injection appears to be an effective esthetic treatment for patients with muscle-induced facial asymmetry.”
“Background: Ventriculostomy-associated infections are a serious

complication of external ventricular drains. The objective of this study was to analyze the clinical features of and risk factors for such infections.

Methods: GSK3326595 ic50 We retrospectively collected demographic and clinical

data on patients with indwelling ventriculostomy catheters hospitalized in a teaching hospital from July 2001 to June 2006, comparing those with and without ventriculostomy-associated infections.

Results: A total of 197 drains (2910 catheter-days) placed in 155 patients were studied. Infections developed in 28 of the 197 (14.2%) drains. The duration from insertion to infection ranged from 7 to 36 days. The cut-off point of duration from insertion to infection was 15.5 days. Re-insertion because of catheter malfunction carried a high risk of infection (p < 0.001). Patients with infections had a longer intensive care unit stay (p = 0.001), longer duration of catheterization Apoptosis Compound Library (p = 0.002), and a higher incidence of concurrent sepsis (p = 0.018), urinary tract infection (p = 0.011) and pneumonia (p = 0.004). Gram-negative bacilli were the leading pathogens

(84%); Pseudomonas aeruginosa was the most common isolate. Polymicrobial infections occurred later than monomicrobial infections (p = 0.003).

Conclusions: Repeated insertion and longer duration of drains are major risk factors for ventriculostomy-associated infections. Crown Copyright (C) 2009 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. All rights reserved.”
“Objectives. The purpose of this study was to evaluate the volumetric changes of the maxillary sinus graft in conjunction with buccal fat pad (BFP) covering the lateral sinus wall.

Study design. In this article, the radiographic results are presented on 11 consecutively treated patients using an equal mixture of the autogenous bone harvested from the tuberosity and natural bone mineral (Bio-Oss) used to augment the maxillary sinus. Buccal fat pad was used over the lateral sinus wall in all cases as a membrane to cover the augmentation material. The mean initial bone height (IBH) was 3.82 mm as measured in the posterior maxilla. Three months after sinus elevation, radiographic evaluation was performed for the patients and secondary bone height was measured (SBH(1)). Fifty-two implants were placed in augmented sinuses. Prosthetic rehabilitation of the patients was done 4 months after inserting the implants.

incognita after 48 h at 0 5% concentration Compounds 1, 2 and 3

incognita after 48 h at 0.5% concentration. Compounds 1, 2 and 3 were found to be more potent than the nematicide Azadirachta indica at the same concentration. Negative results were obtained for nematicidal activity of the petroleum ether extract of R. niveus leaf extract. This is the first report on the isolation of chemical constituents as well as the nematicidal activity of compounds and any part of R. niveus.”
“The early clinical presentations of StevensJohnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are similar to that

of erythema multiforme major (EMM). Cytotoxic molecules, especially granulysin, are expressed in the skin lesions of SJS/TEN and cause extensive keratinocyte death. It is postulated that the function of regulatory T cells (Treg) in SJS/TEN is inadequate. This study examined whether an immunohistological

examination of cytotoxic molecules and the immunophenotype of Treg is useful for discriminating SJS from EMM in the early period. Over the past 9 years, the lesional skin of 14 patients with SJS/TEN and 16 patients with EMM was biopsied. Double immunofluorescence labeling of CD8 and granulysin, perforin, or granzyme B was performed, and immunohistochemical analyses of granulysin, perforin, granzyme B, CD1a, CD3, CD4, CD8, CD68 and Foxp3 were conducted using a highly sensitive indirect immunoperoxidase technique. The number of cells positive for each antibody per five high-power fields was counted. The proportions of granulysin+ cells/CD8+ cells (P = 0.012) and perforin+ cells/CD8+ cells (P = 0.037) in SJS/TEN were significantly Dinaciclib inhibitor Selleckchem SB273005 higher than in EMM. The number of Foxp3+ cells/five high-power fields in SJS/TEN was significantly lower than in EMM (P = 0.004). Similarly, the number of CD4+ cells/five high-power fields in SJS/TEN was significantly lower than in EMM (P = 0.0017). These data suggest that these panels of antibodies for labeling cytotoxic molecules, CD4 and Treg are useful for discriminating early SJS/TEN and EMM with a skin biopsy.”
“Shoot tips of the germinated seeds of Astragalus

sieberi DC. were cultured on MS-medium supplemented with 0.1 mg L-1 each of naphthalene acetic acid (NAA) and benzyl adenine (BA) for establishment of shoot cultures. The effect of different concentrations of growth regulators on saponin content was studied and optimised. Saponin content was monitored by HPLC analysis. The most appropriate growth regulator with which to produce the highest content of saponins in shoot cultures was 0.5 mg L-1 each of NAA and BA. The isolated cycloastragenol-3-O-glucoside was identified by spectral analysis and compared with an authentic sample.”
“In this report, we describe an 88-year-old male stroke patient with unilateral bullous pemphigoid limited to the hemiplegic side.

“Accurate reconstruction of prehistoric social organizatio

“Accurate reconstruction of prehistoric social organization is important if we are to put together satisfactory multidisciplinary scenarios about, for example, the dispersal of human groups. Such considerations apply in the case of Indo-European and Austronesian, two large-scale language families that are thought to represent Neolithic Selinexor expansions. Ancestral kinship patterns have mostly been inferred through reconstruction of kin terminologies in ancestral proto-languages using the linguistic comparative method, and through geographical or distributional arguments based on the comparative patterns of kin terms and ethnographic

kinship ‘facts’. While these approaches are detailed and valuable, the processes through which conclusions have been

drawn from the data fail to provide check details explicit criteria for systematic testing of alternative hypotheses. Here, we use language trees derived using phylogenetic tree-building techniques on Indo-European and Austronesian vocabulary data. With these trees, ethnographic data and Bayesian phylogenetic comparative methods, we statistically reconstruct past marital residence and infer rates of cultural change between different residence forms, showing Proto-Indo-European to be virilocal and Proto-Malayo-Polynesian uxorilocal. The instability of uxorilocality and the rare loss of virilocality once gained emerge as common features of both families.”
“Quinpirole-induced vertical jumping is a phenomenon first observed in rats treated from birth, once a day for 21 days or more, click here with the dopamine D-2 receptor agonist quinpirole. This quinpirole-induced behavioral sensitization is known as a priming process. To determine whether dopaminergic innervation

influenced this priming phenomenon, groups of rats were lesioned at 3 days after birth with the neurotoxin 6-hydroxydopamine (6-OHDA; 67 mu g in each lateral ventricle; desipramine pretreatment, 20 mg/kg ip, 1 h). Rats were additionally treated daily from birth with quinpirole HCl (3.0 mg/kg ip, salt form). Controls received saline vehicle in place of 6-OHDA and/or quinpirole. When rats were placed in individual observation cages (1 h acclimation) starting at 20 days after birth, acute quinpirole treatment produced vertical jumping in the quinpirole-primed group; and the effect persisted through the twenty-ninth day. In rats additionally lesioned with 6-OHDA, vertical jumping was enhanced at 20, 24, 26/27, and 28/29 day-with there being as much as a 32-fold increase in vertical jumping versus the group that was primed with quinpirole, but not lesioned with 6-OHDA. This finding indicates that an ontogenetic 6-OHDA lesion enhances quinpirole-induced vertical jumping in rats and that dopaminergic innervation may normally exert a suppressive effect on vertical jumping.

There were 43 males and 21 females with mean age of 36 years Dur

There were 43 males and 21 females with mean age of 36 years. Duration of symptom

was averaged 42 weeks. The patients were asked to complete questionnaires concerning sexual desire, activity, adjustment, and satisfaction. About 83% of the patients had sexual desire, and 89% achieved satisfaction during sexual activities in presick period.

Results. Lumbar disc herniation decreased sexual desire in 50% and frequency of sexual activity in 59% of the patients. About 67% of males and 81% of females felt discomfort LEE011 nmr during sexual activity; satisfaction decreased in 28% of male and 41% of females. Adjustment in sexual position was required in 54% of males and 86% of females. Surgery improved sexual desire, frequency ON-01910 datasheet of sexual activity, and satisfaction in 85%, 88%, and 94%, respectively. However, 31% of females did not regain sexual desire and 46% still felt discomfort

during sexual activity (the rates were 7% and 17% in males, respectively). Sexual activity was resumed within 2 postoperative weeks in 23% (27% in males and 14% in females), and 4 weeks in 53%. Males resumed sexual activity earlier than females.

Conclusion. Lumbar disc herniation largely impacted sexual desire, activity, and satisfaction. Adjustment in sexual position was required in large number of patients to avoid discomfort during sexual activities. Surgical treatment improved quality of sexual activities, but more females did not regain sexual desire, felt sexual discomfort, and thereby resumed sexual activities later than males after surgery.”
“A positive attitude to patients with mental illness is important in all branches of medicine, as it can impact on the quality of care patients receive from doctors. Attitudes of preclinical medical students is an under researched area.

This study aims to (1) assess the attitudes of preclinical and clinical medical students to patients with mental illness and (2) assess the effect of two modules taught using different teaching methods on students’ attitudes to patients with mental illness.

During the same

academic year all students (N = 394) completing the year 3 preclinical psychiatry module and the final year psychiatry module completed an attitudinal questionnaire at the beginning and following completion of the module. Seventy-two percent of students completed both pre- and post-module questionnaires in full (n = 285).

There was no significant difference in attitudes displayed by preclinical and clinical medical students prior to starting their respective modules. An association was found between female gender and more tolerant attitudes (r = 0.20, p = 0.02). Students who knew someone with experience of mental illness were associated with more tolerant attitudes (r = 0.32, p < 0.001). Final year students who completed the clinical module demonstrated a positive attitudinal shift (p < 0.

On the basis of this study, it has been shown that application of

On the basis of this study, it has been shown that application of insulin

emulgel iontophoretically can be used as alternative (acceptable & painless) to injectable insulin subject to further studies on large animals.”
“Objectives: Satisfactory bonding of orthodontic attachments to amalgam is a challenge for orthodontists. The aim of this in vitro study was to compare the shear bond strength of stainless steel orthodontic Selleckchem Elacridar brackets to silver amalgam treated with sandblasting and Er,Cr:YSGG laser.

Study Design: Fifty-four amalgam discs were prepared, polished and divided into three groups: In group 1 (the control group) the premolar brackets were bonded using Panavia F resin cement without any surface treatment; in groups 2 and 3, the specimens were subjected to sandblasting and Er,Cr:YSGG laser

respectively, before bracket bonding.

After immersing in distilled water at 37 degrees C for 24 hours, all the specimens were tested for shear bond strength. Bond failure sites were evaluated under a stereomicroscope. Data was analyzed using one-way ANOVA and a post hoc Tukey test.

Results: The highest and lowest shear bond strength values were recorded in the laser and control groups, respectively. There were significant differences in mean shear bond strength values between the laser and the other two groups (p<0.05). However, there were no significant differences between the sandblast and Saracatinib control groups (p=0.5).

Conclusions: Amalgam surface treatment with Er,Cr:YSGG laser increased shear bond strength of stainless steel orthodontic brackets.”
“The modular concept of cerebellar connections has been advocated in the lifetime work of Jan Voogd. In this concept, a cerebellar Selleck LDN-193189 module is defined as the conglomerate of one or multiple and non-adjacent, parasagittally arranged zones of Purkinje cells, their specific projection

to a well-defined region of the cerebellar nuclei, and the climbing fiber input to these zones by a well-defined region of the inferior olivary complex. The modular organization of these olivo-cortico-nuclear connections is further exemplified by matching reciprocal connections between inferior olive and cerebellar nuclei. Because the different regions of the cerebellar nuclei show highly specific output patterns, cerebellar modules have been suggested to constitute functional entities. This idea is strengthened by the observation that anatomically defined modules adhere to the distribution of chemical markers in the cerebellar cortex suggesting that modules not only differ in their input and output relations but also may differ in operational capabilities. Here, I will briefly review some recent data on the establishment of cerebellar modules in rats. Furthermore, some evidence will be shown suggesting that the other main afferent system (i.e., mossy fibers), at least to some extent, also adheres to the modular organization.

Here, we investigated the evaluation of therapeutic efficacy by m

Here, we investigated the evaluation of therapeutic efficacy by molecular imaging in reporter gene transfected tumor xenografts using a gamma imaging system.

Methods: The hNIS gene was transfected into MDA-MB-231 cells using Lipofectamine. The correlation between the number of MDA-MB-231-hNIS cells and the uptake

of Tc-99m-pertechnetate BAY 1895344 in vitro or I-125 was investigated in vitro by gamma imaging and counting. MDA-MB-231-hNIS cells were injected subcutaneously into mice. When the tumor volume reached 180-200 mm(3), we randomly assigned five animals to each of three groups representing different tumor therapies; no DC101 (control), 100 mu g, or 150 mu g DC101/mouse. One week and 2 weeks after the first injection of DC101, gamma imaging was performed. Mice were sacrificed 2 weeks after the first injection of DC101. The tumor tissues were used for reverse transcriptase-polymerase chain reaction (RT-PCR) and CD31 staining.

Results: Uptake of I-125 and Tc-99m-pertechnetate into MDA-MB-231-hNIS cells in vitro showed correlation with the number of cells. In DC101 treatment groups, the mean tumor volume was smaller than that of the control mice. Furthermore,

tumor uptake of I-125 was lower than in the controls. The CD31 staining and RT-PCR assay results showed that vessel formation and expression AMG510 cell line of the hNIS gene were significantly reduced in the tumor tissues of treatment groups.

Conclusion: This study demonstrated the power of molecular

imaging using a gamma imaging system for evaluating the therapeutic efficacy of an antitumor treatment. Molecular imaging systems may be useful in evaluation and development of effective diagnostic and/or therapeutic antibodies for specific target molecules. (C) 2011 Elsevier Inc. All rights reserved.”
“Objective: To determine the impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation.

Methods: From January 1, 1993, to April 30, 2009, a total of 525 cardiac transplants were performed. Ventricular assist devices GSK690693 chemical structure were placed as a bridge to transplant in 110 patients. We focused our analysis on the 2 most common causes of end-stage heart failure requiring transplantation: idiopathic dilated cardiomyopathy (n = 201) and coronary artery disease (n = 213). Data including gender, age, date of transplant, cause of heart failure, prior heart transplant, placement of a ventricular assist device, type of ventricular assist device, and panel-reactive antibody sensitization were analyzed to derive Kaplan-Meier survival probabilities and multivariable Cox regression models.

Results: In patients with idiopathic dilated cardiomyopathy who received a ventricular assist device as a bridge to transplant, survival was decreased at 1 year (P = .008) and 5 years (P = .019), but not at 10 years, posttransplant.