We have earlier shown that AMPA treatment attenuated GSK3 beta activity. Our data suggest that AMPA reduces the cell surface expression of NMDA receptors TPCA-1 datasheet through the regulation of GSK3 beta and, consequently, reduces the amount of intracellular Ca(2+). NeuroReport
20:161-165 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“Routine use of the automated chemiluminescent microparticle immunoassay Abbott ARCHITECT (R) anti-HBc for diagnosis of hepatitis B is limited in case of borderline reactive sera with low signal close to the cut-off index. In order to determine the significance of anti-HBc detection when borderline reactivity occurs using the ARCHITECT (R) anti-HBc assay, a comparative study was designed. 3540 serum samples collected over a 2-month period in the Torin 1 nmr hospital of Nice were examined for markers of HBV infection (HBsAg, anti-HBs and anti-HBc). One hundred seven samples with sufficient volume and with borderline reactivity by the ARCHITECT (R) assay were tested by two other anti-HBc assays, a microparticle enzyme immunoassay
(MEIA, AxSYM (R) Core (TM), Abbott Laboratories, IL, USA) and an enzyme linked fluorescent assay (ELFA, VIDAS (R) Anti-HBc Total II, bioMerieux, Lyon, France). Only 46 samples were confirmed by the AxSYM (R) and the VIDAS (R) assays. Additional serological information linked to patient history showed that the remaining samples (61) were false positives (11), had low titer of anti-HBc antibodies (13), or were inconclusive (37). This comparative study highlighted the existence of a grey zone around the cut-off index. Confirmative results through a different immunoassay are needed to confirm the diagnosis of HBV on borderline reactive sera using the ARCHITECT (R) anti-HBc assay. PIK3C2G (C) 2008 Elsevier B.V. All rights reserved.”
“The relative latencies of evoked electroencephalogram potentials to lateralized visual stimuli were used to calculate the interhemispheric transfer time (IHTT) in right-handed and left-handed males. We confirmed earlier observations of a directional asymmetry in right-handed
males. That is, IHTT from the right to the left hemisphere is significantly shorter than from the left to the right We showed for the first time, however, that this directional asymmetry is not seen in left-handed males. It is suggested that differences in the cytoarchitechtonics of the right and left hemisphere (differences that may result in lateralization of function per se) underlie the asymmetric IHTT in right handers, and that these differences are less pronounced in left handers. NeuroReport 20:166-169 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“The early diagnosis of human cytomegalovirus (CMV) infection in immunosuppressed patients has been improved by molecular detection of CMV DNA.