Salmonella O47 has the same O-unit backbone and a similar O-antigen gene cluster (OGC) (the DNA identity ranges from 74% to 83%) as E. coli O118 and O151. It was suggested that the OGCs of the three bacteria studied originated from a common ancestor.”
“Objectives: The clinical impact of seasonal influenza is understudied in tropical countries. The aim of this study was to describe the clinical features and seasonal pattern of influenza in children hospitalized in selleck compound Malaysia, and to identify predictors of severe disease.

Methods: Children hospitalized with community-acquired, laboratory-confirmed influenza at a teaching hospital in Kuala Lumpur, Malaysia during 2002-2007 were identified

retrospectively. Clinical data were collected, and predictors of severe disease were identified by multivariate logistic regression. All influenza cases from 1982 to 2007 were also analyzed for seasonal patterns.

Results: A total of 132 children were included in the study, 48 (36.4%) of whom had underlying medical conditions. The

mean age was 2.5 years and 116 (87.9%) were < 5 years old. The most common presenting features were fever or history of fever, cough, rhinitis, vomiting, and pharyngitis. Severe influenza was seen in 16 patients (12.1%; nine previously healthy), including 12 (9.1%; eight previously healthy) requiring intensive care. There were three (2.3%) deaths. Severe disease was associated with age <

12 months, female sex, and find more absence of rhinitis on admission. Influenza was seen year-round, with peaks in November-January and May-July.

Conclusions: Seasonal influenza has a considerable impact on children hospitalized in Malaysia, in both the healthy and those with underlying medical conditions. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.”
“A 52-year-old man had uneventful bilateral myopic laser in situ keratomileusis (LASIK) with planned monovision. Three months later, the left eye was retreated to improve the near vision. On postoperative day 1, the uncorrected distance visual acuity (UDVA) was 0.95 and the patient reported mild ocular pain. Stage 2 diffuse lamellar keratitis was observed. Despite hourly Kinase Inhibitor Library prednisolone instillation, the UDVA decreased to 0.1 and central flap necrosis syndrome was diagnosed. The flap was lifted and stromal bed irrigation performed. One month later, the UDVA was 0.05 with a hyperopic shift of +3.25 diopters and the flap, which had central haze and several striae, was amputated. Four months later, the UDVA was 0.05 with residual irregular astigmatism. Customized transepithelial photorefractive keratectomy (PRK) was performed; there were no postoperative complications. Three months after PRK, the UDVA was 0.8 with no refractive defect.