METHODS
We investigated the relationship between the superior auricular artery and its surrounding structures through anatomic studies with seven fresh cadavers and applied the findings clinically. From February 2008 to December Taselisib inhibitor 2009, we performed 12 cases with the superior
auricular artery island flap to reconstruct defects in the upper region of the auricle and its surroundings.
RESULTS
We found that the superior auricular artery is a reliable pedicle for the retroauricular flap. All wounds of the patients were successfully closed, with the exception of one minor complication. The aesthetic outcomes of the donor and recipient sites were satisfactory.
CONCLUSIONS
The superior auricular artery island flap has several advantages. Therefore, we suggest that the superior auricular artery island flap can be another choice for reconstructing soft tissue defects at the upper region of the auricle and its surrounding area.
The authors have indicated no significant interest with commercial supporters.”
“Study Design. Case report.
Objective. To retrieve data about the utility of intrathecal baclofen for the treatment of otherwise refractory priapism that may occur in patients with spinal spasticity.
Summary
GSK1120212 inhibitor of Background. Baclofen exerts well-known inhibitory effects on sexual function both in animals and humans. This observation led to the introduction of oral baclofen in the treatment of refractory and recurrent idiopathic priapism.
Methods. We report a 41-year-old male patient who sustained a severe traumatic spinal cord injury in a motor vehicle accident. On clinical examination he presented with tetraplegia (motor level C3). Initial cervical magnetic resonance imaging showed a C3 to C4 lesion
with a herniated disc and compression of the dural sac. One month later the patient developed priapism episodes.
Results. Elacridar datasheet He received oral baclofen with only minimal beneficial effect on priapism. Eight months postinjury the patient underwent a test-trial with intrathecal baclofen bolus, which caused absence of priapism for 10 hours. One month later, an intrathecal pump system was implanted, leading to absence of priapism episodes.
Conclusion. In the present case report, reduction of supraspinal control on the spinal cord may have induced an up-regulation of GABAB receptors, which are involved in penile tumescence. The trauma induced also liberation of penile reflexes with episodes of priapism. Normal full blood count and color duplex ultrasonography of the penis excluded a vascular genesis of priapism. This is the first report about the utility of intrathecal baclofen for the successful control of otherwise untreatable priapism in a patient with severe spinal spasticity.