In the third trimester, the differential diagnosis is more challenging for the obstetrician and the nephrologist and comprises some pathologies that are reviewed in this article: preeclampsia/HELLP syndrome, acute fatty liver of pregnancy and thrombotic microangiopathies.”
“Objective: To study the prediction of low birth weight (LBW) using modified Indian Council of Medical Research (ICMR) antenatal scoring method. \

Method: The present longitudinal study was carried out amongst

1138 pregnant women residing in area covered by Kinaye primary health LY2835219 concentration centre (PHC) in rural Karnataka, India.

Results: Modified ICMR risk scoring revealed that 597 (52.5%) women had a risk score 6-10 (mild risk), 142 (12.5%) women had risk score 11-15 (moderate risk) and 29 (2.5%) had risk score >= 16 (severe risk), whereas, remaining 370 (32.5%) had a score of 0-5 considered as “”no risk group”". The incidence of LBW had direct relationship with the risk score. buy Compound Library The sensitivity was high (80.6%), whereas, specificity was slightly low (70.4%),

positive predictive value was low (43.8%) and negative predictive value high (92.7%) for LBW when the risk score cut-off point was >7.

Conclusion: The modified ICMR antenatal scoring method can be used at all levels of health care and is an ideal instrument for prediction of LBW at the community level. It can be easily applied by even a health worker, not time consuming and at the same time does not lose its predictability.”
“We report for the first time a patient with both transient neonatal diabetes mellitus (TNDM) and idiopathic find more neonatal cholestasis, with both features resolving over a similar time. course. Cholestasis was due to paucity of interlobular bile ducts (PILBD). Genetic analysis was consistent with a uniparental disomy of chromosome 6 Paucity of interlobular bile ducts is common in Alagille syndrome but also occurs by unknown mechanisms in a wide spectrum of other

diseases We propose a shared explanation for this patient’s TNDM and PILBD mediated by the noted chromosomal abnormality We suggest that hepatobilary function be evaluated in patients with TNDM to determine the prevalence and course of cholestasis of the disease.”
“Gonadal dysfunction is a frequent finding in men with chronic kidney disease and with end-stage renal disease. Testosterone deficiency, usually accompanied by elevation of serum gonadotropin concentrations, is present in 26-66% of men with different degrees of renal failure. Uremia-associated hypogonadism is multifactorial in its origin, and rarely improves with initiation of dialysis, although it usually normalizes after renal transplantation.