Br J Cancer 2006, 94: 128–135.CrossRefPubMed 18. Tandon AK, Clark GM, Chamness GC, Ullrich A, McGuire WL: HER-2/neu oncogene protein and prognosis in breast cancer. J Clin Oncol 1989, 7: 1120–1128.PubMed 19. Litvinov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO: Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. J Cell Biol
1994, 125: 437–446.CrossRefPubMed 20. Lohrisch C, Piccart M: An overview of HER2. Semin Oncol 2001, 28: 3–11.CrossRefPubMed 21. Heiss MM, Strohlein MA, Jager M, Kimmig R, Burges A, Schoberth A, et al.: Immunotherapy of malignant ascites with trifunctional antibodies. Int J Cancer 2005, 117: 435–443.CrossRefPubMed 22. Burges A, Wimberger P, Kumper C, Gorbounova Roscovitine order V, Sommer H, Schmalfeldt B, et al.: Effective relief of malignant ascites in patients with advanced ovarian
cancer by a trifunctional anti-EpCAM × anti-CD3 antibody: a phase I/II study. Clin Cancer Res 2007, 13: 3899–3905.CrossRefPubMed 23. Allgayer H, Babic R, Gruetzner KU, Tarabichi A, Schildberg FW, Heiss MM: c-erbB-2 is of independent prognostic relevance in gastric cancer and is associated with the expression of tumor-associated protease systems. J Clin Oncol 2000, 18: 2201–2209.PubMed 24. Lewis LD, Cole BF, Wallace PK, Fisher JL, Waugh M, Guyre PM, et al.: Pharmacokinetic-pharmacodynamic Angiogenesis inhibitor relationships of the bispecific antibody MDX-H210 when administered in combination with interferon gamma: a multiple-dose phase-I study in patients with advanced cancer which overexpresses HER-2/neu. J Immunol Methods 2001, 248: 149–165.CrossRefPubMed 25. Joplin R, Strain AJ, Neuberger JM: Biliary epithelial cells from the liver of patients with primary biliary cirrhosis: isolation, characterization, and short-term C59 culture. J https://www.selleckchem.com/HSP-90.html Pathol 1990, 162: 255–260.CrossRefPubMed 26. de Gast GC, Haagen IA, van Houten AA, Klein SC, Duits AJ, de Weger RA, et al.: CD8 T cell activation after intravenous administration of CD3 × CD19
bispecific antibody in patients with non-Hodgkin lymphoma. Cancer Immunol Immunother 1995, 40: 390–396.CrossRefPubMed 27. Canevari S, Stoter G, Arienti F, Bolis G, Colnaghi MI, Di Re EM, et al.: Regression of advanced ovarian carcinoma by intraperitoneal treatment with autologous T lymphocytes retargeted by a bispecific monoclonal antibody. J Natl Cancer Inst 1995, 87: 1463–1469.CrossRefPubMed 28. Kroesen BJ, Bakker A, van Lier RA, The HT, de Leij L: Bispecific antibody-mediated target cell-specific costimulation of resting T cells via CD5 and CD28. Cancer Res 1995, 55: 4409–4415.PubMed 29. Deo YM, Graziano RF, Repp R, Winkel JG: Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies. Immunol Today 1997, 18: 127–135.CrossRefPubMed 30. Schweizer C, Strauss G, Lindner M, Marme A, Deo YM, Moldenhauer G: Efficient carcinoma cell killing by activated polymorphonuclear neutrophils targeted with an Ep-CAMxCD64 (HEA125 × 197) bispecific antibody. Cancer Immunol Immunother 2002, 51: 621–629.CrossRefPubMed 31.