4 kOe, and then decreases. Further SEM observation indicates that the microstructure of the optimal ribbons was composed of fine and uniform crystal grains, which was responsible for the ultrahigh intrinsic coercivity of the ribbons. (C) 2011 American Institute of Physics. [doi:10.1063/1.3567144]“
“Globozoospermia is a human infertility syndrome caused by spermatogenesis defects (OMIM 102530). Acrosome plays an important role at the site of sperm-zonapellucida binding during the fertilization process. Thus, malformation of the acrosome buy VX-680 is the most prominent feature seen in globozoospermia. Disruption of several mouse genes, including Gopc (Golgi-associated PDZ and coiled-coil

motif containing protein), Hrb (HIV-1 Rev binding protein), Csnk2a2 (casein

kinase 2, alpha prime polypeptide) and Pick1 (protein interacting with C kinase 1), results in a phenotype similar to globozoospermia in humans, which suggests their potential role in the disease. However, no mutations with a clear link to globozoospermia have been identified in these genes in humans. In this study, we screened the candidate genes mentioned above in three globozoospermia type I patients and discovered a homozygous missense mutation (G198A) in exon 13 of the PICK1 gene in a Chinese family. The family member affected by this homozygous missense mutation showed a complete lack of acrosome. Using the candidate gene screening strategy, CAL-101 manufacturer our study is the first to identify an autosomal recessive genetic mutation in PICK1 that was responsible for globozoospermia in humans.”
“Panic disorder has an elevated prevalence in Parkinson’s disease (PD). To explore the basis for this co-occurrence, the familial aggregation of panic disorder was examined in patients with PD. Probands and relatives of patients with PD and panic disorder (PD-PANIC; CYT387 supplier N=20, N=115) and control probands with PD and no active psychiatric

illness (PD-NA; N=17, N=108) were interviewed by phone, using a structured interview to determine panic status. Lifetime prevalence of panic and “”panic-like”" disorders was higher in PD-PANIC than in PD-NA relatives. Panic and “”panic-like”" disorders are familial disorders in PD. (The Journal of Neuropsychiatry and Clinical Neurosciences 2011; 23:417-424)”
“The effect of the atomic disorder-order transformation on the interaction mechanisms in isotropic PtCo alloys has been studied by isothermal annealing at 953 K, well below the transformation temperature, for 5-30 min after quenching from 1273 K. The transmission electron microscopy (TEM) testing showed that the ordered regions grew with prolonging heat treatment time. Investigation of the interaction mechanisms in PtCo alloys has been made using analysis of the delta M(H) plot. The results of the delta M(H) plot and TEM indicate that the interaction mechanisms are changed by the size of the magnetically soft and hard phases.