Using prospectively collected data on neonatal admissions to a rural district hospital in a region of stable malaria
endemicity in Kenya, the prevalence of congenital and neonatal malaria was described.
Methods: From 1(st) January 2002 to 31(st) December 2009, admission and discharge information on all neonates admitted to Kilifi District Hospital was collected. At admission, blood was also drawn for routine investigations, which included a full blood count, blood culture and blood slide for malaria parasites.
Results: Of the 5,114 neonates admitted during the eight-year surveillance period, blood slide for malaria parasites was performed in 4,790 (93.7%). 18 (0.35%) neonates with Plasmodium falciparum malaria parasitaemia, EPZ5676 inhibitor of whom 11 were admitted within the first week of life and thus classified as congenital parasitaemia, were identified. 7/18 (39%) had fever. Parasite densities
were low, <= 50 per mu l in 14 cases. The presence of parasitaemia was associated with low haemoglobin (Hb) of <10 g/dl (chi(2) 10.9 P = 0.001). The case fatality rate of those with and without parasitaemia was similar. Plasmodium falciparum parasitaemia was identified as the cause of symptoms in four neonates.
Conclusion: PI3K inhibitor Congenital and neonatal malaria are rare in this malaria endemic region. Performing a blood slide for malaria parasites among sick neonates in malaria endemic regions is advisable. This study does not support routine treatment with anti-malarial drugs among admitted neonates with or without fever even in a malaria endemic region.”
“A hospital-based investigation was conducted to understand the epidemiologic profile of rotavirus diarrhea due to community-acquired and hospital-acquired infection among children >28 days of age, between November 2006 and January 2008 in Shanghai. Rotavirus infection was related
to 37.2% of clinic visit and 48.1% of ward admission attributable to community-acquired noninvasive bacterial diarrhea among Shanghainese selleck compound children. Rotavirus was responsible for 54.8% of nosocomial diarrhea. G3P[8] (56.8%) was the most prevalent, followed by G1P[8] (15.8%), G2P[4] (3.0%), and G9P[8] (2.3%).”
“Background: It is increasingly recognized that the impact of disease on quality of life should be taken into account when assessing health status. It is likely that tooth loss, in most cases being a consequence of oral diseases, affects Oral Health-Related Quality of Life (OHRQoL). The aim of the present study is to systematically review the literature and to analyse the relationship between the number and location of missing teeth and oral health-related quality of life (OHRQoL). It was hypothesized that tooth loss is associated with an impairment of OHRQoL. Secondly, it was hypothesized that location and distribution of remaining teeth play an important role in this.