CJASN. 2009;4:S12–7.PubMed 46. Cooper BA, Branley P, Bulfone L, et al. A randomized, controlled trial of early versus late initiation of dialysis. N Engl J Med. 2010;363:609–19.PubMedCrossRef 47. Rosansky SJ, Eggers P, Jackson K, et al. Early start of hemodialysis may be harmful. Arch

Int Med. 2011;171:396–403.CrossRef 48. Yamagata K, Nakai S, Masakane I, et al. Ideal timing and predialysis nephrology care duration for dialysis initiation; from analysis of Japanese Dialysis initiation survey. Ther Apher Dial. 2012;16:54–62.PubMedCrossRef 49. Yamagata K, Nakai S, Iseki K, et al. Late dialysis start did not affect long-term outcome in Japanese dialysis patients: long-term prognosis from Japanese Society of Dialysis Therapy Registry. Ther Apher Dial. 2012;16:111–20.PubMedCrossRef 50. Japanese Society of Nephrology. Clinical practice guidebook for diagnosis and treatment SCH772984 in vitro of chronic kidney disease. Tokyo: Tokyo Igakusha; 2012. 51. Japanese Society of Nephrology. Evidence-based practice guideline for the treatment of CKD. Tokyo: Tokyo Epacadostat nmr Igakusha; 2009. 52. Yamagata K, Makino H, Akizawa T, et al. Design and methods of a strategic outcome study for chronic kidney

disease—frontier of renal outcome modifications in Japan (FROM-J). Clin Exp Nephrol. 2010;14:144–51.PubMedCrossRef 53. Iseki K, Asahi K, Moriyama T, et al. Risk factor profiles based on eGFR and selleck chemicals dipstick proteinuria: analysis of the participants of the Specific Health Check and Guidance System in Japan 2008. Clin Exp Nephrol. 2012;16:244–9.PubMedCrossRef 54. Sugiyama H, Yokoyama H, Sato H, et al. Japan Renal Biopsy Registry: the first nationwide, web-based, MycoClean Mycoplasma Removal Kit and prospective registry system of renal biopsies in Japan. Clin Exp Nephrol. 2011;15(4):493–503.PubMedCrossRef 55. Yokoyama H, Sugiyama H, Sato H, et al. Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). Clin Exp Nephrol. 2012;16:903–20.PubMedCrossRef 56. Levey A, de Jong PE, Coresh J, et al. Chronic kidney disease—definition, classification and prognosis: a KDIGO controversies

conference report. Kidney Int. 2011;80:17–28.PubMedCrossRef 57. Van der Velde M, Matsushita K, Coresh J, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int. 2011;79:1341–52.PubMedCrossRef 58. Gansevoort RT, Matsushita K, van der Velde M, et al. Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts. Kidney Int. 2011;80:93–104.PubMedCrossRef 59. Astor BC, Matsushita K, Gansevoort RT, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int.