There are several unique features of the study region. Most notably, compared with other areas, it has little general outward migration and only includes a small ethnic minority community. We anticipate that the registry will provide an important regional data source for research, audit and service provision planning. The importance of regional PARP inhibitor registries is now being

recognised, and we hope that a description of our recent experience will be useful to individuals involved in registry development elsewhere. Copyright © 2013 John Wiley & Sons. “
“Professional cycling is one of the most physically demanding endurance sports. While literature exists on the needs of people with diabetes during exercise and sport of low to medium levels of intensity, there is less information around specific needs during endurance sports, and little published information on professional endurance sports. The approach to diabetes management taken by a professional cycling team comprised solely of people with type 1 diabetes provides useful insight for health care professionals with patients wanting to take up competitive sport or exercise at more intense levels. A systematic approach to achieving tight glycaemic control is taken that includes monitoring and analysis

of blood glucose levels before, during and after training and competition, and a structured and balanced nutrition and race management plan. With support from experienced health care professionals, intense physical activity and endurance sports can be an option for individuals with diabetes, GSK2126458 supplier as long as they are educated about their condition and disciplined and committed to achieving glycaemic control. Orotidine 5′-phosphate decarboxylase Copyright © 2013 John Wiley & Sons. “
“Patients with diabetes have long been exhorted to give up sugar, encouraged instead to take in fuel as complex carbohydrate such as the starch found in bread, rice or pasta (especially if ‘wholemeal’). However, bread has a higher glycaemic index than table sugar itself. There are no essential nutrients in starchy foods and people with diabetes struggle to deal with

the glycaemic load they bring. The authors question why carbohydrate need form a major part of the diet at all. The central goal of achieving substantial weight loss has tended to be overlooked. The current pilot study explores the results of a low carbohydrate diet for a case series of 19 type 2 diabetes and pre-diabetes patients over an eight-month period in a suburban general practice. A low carbohydrate diet was observed to bring about major benefits. Blood glucose control improved (HbA1c 51±14 to 40±4mmol/mol; p<0.001). By the end of the study period only two patients remained with an abnormal HbA1c (>42mmol/mol); even these two had seen an average drop of 23.9mmol/mol. Weight fell from 100.2±16.4 to 91.0±17.